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- $Unique_ID{BRK02053}
- $Pretitle{}
- $Title{Pancreas Transplantation and Future Treatments for Severe Diabetes}
- $Subject{diabetes diabetic insulin injections pancreas transplants kidney
- transplant surgery transplantation surgeries kidney failure xenografting
- Islands of Langerhans islet cells}
- $Volume{}
- $Log{
- The Islets of Langerhans*0002905.scf
- Anatomy of the Kidney*0004801.scf
- Cross Section of a Kidney*0004901.scf
- Structure of the Pancreas*0009801.scf
- Diabetes Mellitus*0009802.scf
- The Functions of Insulin*0009803.scf
- Anatomy of the Pancreas*0016601.scf}
-
- Copyright (c) 1993 Tribune Media Services, Inc.
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- Pancreas Transplantation and Future Treatments for Severe Diabetes
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- QUESTION: My sister's diabetes is not being kept under control by her current
- treatments using insulin injections. She is still a young woman in reasonably
- good health, but we fear that in the future she faces gradually declining
- health. Have you heard anything about pancreas transplants, and do you think
- that she should consider this operation? Her family is behind her with all
- the support she needs, but we need advice and information. Won't you please
- help us?
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-
- ANSWER: Pancreas transplantation is not yet considered as an option for
- diabetic patients whose principle problem is one of control. The first
- experimental transplants using organs from deceased donors began in 1966,
- and was first considered proven enough to be considered as a "treatment" in
- 1986. Although almost 65 institutions around the United States now perform
- these pancreas transplants, almost all these operations are reserved for
- individuals who are to receive a kidney transplant.
- Diabetics who have had pancreas transplants are already suffering from
- the complications of advanced diabetes. About 85 percent of these transplants
- are still functioning well a year after the operation, and the progress of the
- complications has been slowed. However, such transplants for people without
- kidney failure are still considered experimental, and are available only in a
- few specialized research centers.
- Current investigations to solving the problems of severe diabetes with
- transplants are now looking to using the tissue from animals (xenografting).
- The cells of the Islands of Langerhans (islet cells) in the pancreas produce
- insulin, and the insulin produced by these cells in pigs is very close to that
- of human insulin. However, since human immune systems reject tissue from
- other species, or even other individuals, this research must first overcome
- rejection failures before this new technique could become available, and this
- may not occur for years, if ever. Your sister therefore must concentrate her
- efforts on controlling her diabetes through those treatments now available:
- insulin, exercise, and proper diet.
-
- ----------------
-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
-